A Striking Response to Lithium in Kleine–Levin Syndrome
نویسندگان
چکیده
منابع مشابه
A Striking Response to Lithium in Kleine–Levin Syndrome
Kleine-Levin syndrome (KLS) is an episodic hypersomnia with cognitive disturbances such as confusion, apathy, and derealization. Hyperphagia and hypersexuality occur in around 50% of cases. No evidence-based treatments have been established for KLS. Many drugs have been tried, most often with little success. Here, a case with a striking response to lithium is presented.
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Background: Lithium is a therapeutic option for the treatment of the acute phase of the bipolar disorder and long-term management of this disorder. However, it is estimated that 10 to 60% of patients do not properly response to this medication. Methods: To investigate the role of MARK2 gene in response to lithium, we genotyped the MARK2 rs10792421 polymorphism in Iranian bipolar pa...
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OBJECTIVE Although sex differences occur with some psychotropic drug treatments, they are not well defined for mood-stabilizing agents, including lithium. The authors' goal was to investigate whether there are differences between the sexes in response to lithium. METHOD Studies identified in a literature search were analyzed for reports of sex differences in clinical response to lithium in ma...
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ژورنال
عنوان ژورنال: Frontiers in Neurology
سال: 2014
ISSN: 1664-2295
DOI: 10.3389/fneur.2014.00033